{"id":447,"date":"2020-04-07T14:58:04","date_gmt":"2020-04-07T14:58:04","guid":{"rendered":"https:\/\/www.cmtc.nl\/?page_id=447"},"modified":"2025-05-14T16:54:12","modified_gmt":"2025-05-14T14:54:12","slug":"diffuse-capillary-malformation-with-overgrowth-dcmo","status":"publish","type":"page","link":"https:\/\/www.cmtc.nl\/en\/pedia\/conditions\/diffuse-capillary-malformation-with-overgrowth-dcmo\/","title":{"rendered":"Diffuse Capillary Malformation with Overgrowth (DCMO)"},"content":{"rendered":"<p>In 2013 a new vascular anomaly was proposed by Margaret S. Lee et al. (1) as an independent entity within the wide spectrum of vascular abnormalities associated with overgrowth.<\/p>\n<p>The new disorder \u2018Diffuse Capillary Malformation with Overgrowth\u2019 (DCMO) did not fit the criteria for known disorders with capillary malformation and\/or overgrowth and therefore is seen as a separate disorder.<\/p>\n<p>DCMO patients have an extensive, diffuse, reticulate capillary malformation (CM) and variable hypertrophy without major complications. It is distinguished by erythematous-purplish stains, with a narrow network morphology than can go with a more homogeneous or plain macules. It has a diffuse distribution, extending minimum beyond one anatomic region, and neither atrophy nor ulcers are present. It has been observed a midline sharply demarcation on the abdomen, but never on the back. The associated overgrowth is a diffuse proportional enlargement of a body region, most commonly of a limb, that does not progress, accordingly vascular or infectious complications will not take place. The skin vascular malformations frequently lighten over the first several months, however less intense than CMTC.<\/p>\n<h2>Articles &amp; video<\/h2>\n<h3>Articles<\/h3>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31909475\/\" target=\"_blank\" rel=\"noopener\">Diffuse capillary malformation with overgrowth contains somatic PIK3CA variants<\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29203436\/\" target=\"_blank\" rel=\"noopener\">A cross-sectional survey of long-term outcomes for patients with diffuse capillary malformation with overgrowth<\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28822558\/\" target=\"_blank\" rel=\"noopener\">Wilms tumor screening in diffuse capillary malformation with overgrowth and macrocephaly-capillary malformation: A retrospective study<\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31909475\/\" target=\"_blank\" rel=\"noopener\">Diffuse capillary malformation with overgrowth contains somatic PIK3CA variants<\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29203436\/\" target=\"_blank\" rel=\"noopener\">A cross-sectional survey of long-term outcomes for patients with diffuse capillary malformation with overgrowth<\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28822558\/\" target=\"_blank\" rel=\"noopener\">Wilms tumor screening in diffuse capillary malformation with overgrowth and macrocephaly-capillary malformation: A retrospective study<\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31909475\/\" target=\"_blank\" rel=\"noopener\">Diffuse capillary malformation with overgrowth contains somatic PIK3CA variants<\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29203436\/\" target=\"_blank\" rel=\"noopener\">A cross-sectional survey of long-term outcomes for patients with diffuse capillary malformation with overgrowth<\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28822558\/\" target=\"_blank\" rel=\"noopener\">Wilms tumor screening in diffuse capillary malformation with overgrowth and macrocephaly-capillary malformation: A retrospective study<\/a><\/p>\n<h3>Video<\/h3>\n<p>No video material available yet.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In 2013 a new vascular anomaly was proposed by Margaret S. Lee et al. (1) as an independent entity within the wide spectrum of vascular abnormalities associated with overgrowth. The new disorder \u2018Diffuse Capillary Malformation with Overgrowth\u2019 (DCMO) did not fit the criteria for known disorders with capillary malformation and\/or overgrowth and therefore is seen [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":2480,"parent":72878,"menu_order":6,"comment_status":"closed","ping_status":"closed","template":"aw-modules\/awcf_create_page_templates_with_elementor_content\/page-templates\/page-aw-page-template-67351.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-447","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Diffuse Capillary Malformation with Overgrowth (DCMO) - CMTC-OVM<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cmtc.nl\/en\/pedia\/conditions\/diffuse-capillary-malformation-with-overgrowth-dcmo\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Diffuse Capillary Malformation with Overgrowth (DCMO) - CMTC-OVM\" \/>\n<meta property=\"og:description\" content=\"In 2013 a new vascular anomaly was proposed by Margaret S. 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