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New medication development: RLY-2608

One of the programs of the company Relay is focused on PIK3CA-driven vascular malformations, including PIK3CA Related Overgrowth Spectrum, known as PROS, and PIK3CA-driven lymphatic malformations. Examples are eg. Klippel-Trenaunay, CLOVES, FAVA, MCAP and many more. The PIK3CA gene creates a protein, called PI3Kα. PI3Kα is involved in your body’s natural cell growth and metabolism. […]

The digital dermatosis – Social media’s unintended impact on pre-adolescent skincare

Social media platforms, particularly TikTok, Instagram, and Snapchat, have become pervasive sources of information and influence, extending significantly into the realm of skincare and cosmetic procedures. While offering avenues for beauty exploration, their impact on pre-adolescent populations, characterized by developing skin and impressionable minds, presents increasing dermatological and psychosocial concerns. This review synthesizes recent findings […]

New: venous malformations and thrombosis

Dr. Maroeska te Loo gave a presentation in Berlin in February 2025 about venous malformations and the risk of thrombosis (clot that obstructs normal blood flow). More information

CMTC-OVM Activities Team (CAT)

CMTC-OVM Activities Team (CAT) We recently established the CMTC-OVM Activities Team.We are involved in so many events and activities that it has become necessary to form a dedicated team. The number of volunteers is growing, with people joining us from both inside and outside our organization. This allows us to divide the workload into smaller, […]

World Health Assembly Resolution on Skin Diseases

Addressing the Need For Global Public Health Priority of Skin Diseases Côte d’ Ivoire, together with Nigeria, Togo, Micronesia, China, Egypt and Colombia is leading an initiative to place skin diseases firmly on the global public health agenda and have proposed a World Health Assembly Resolution on “Skin diseases as a global public health priority ”. […]

Rare disease day 2025

On February 28, 2025, during the National Rare Disease Day Event at Soestdijk Palace, the prestigious Rare Angel Awards were presented to Karin Veldman, Rianne Oostenbrink, and 3FM Serious Request. National Rare Disease Day Event The National Rare Disease Day Event takes place every last day of February as part of International Rare Disease Day. […]

Skin at school

The implementation of the “Skin at School” program in the Netherlands is motivated by several factors. Skin complaints are often underestimated, which affects the quality of life of people with chronic conditions and contributes to significant bullying problems in children. In every classroom there are children who suffer from skin problems such as warts, athlete’s […]

Mental Health & Wellbeing

Eurordis

The European Organization for Rare Diseases (Eurordis) has developed a wonderful website with a wealth of resources on mental health and well-being. We have also participated in this project. The relationship between physical and mental health is well-documented. An increase in the severity and complexity of a physical condition increases the risk of mental health […]

Policy vision on centers of expertise for rare diseases 2025

ERN

An expertise center for a rare disease is often a facility within a hospital that specializes in a specific rare condition. To gain recognition as an expertise center, an application can be submitted to the Ministry of Health, Welfare, and Sport (VWS). With this recognition, an institution can join a European Reference Network (ERN), allowing […]

CMTC
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